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What do you lead? Part V – Leading People: Questions to Ask
When I start a leadership coaching or workshop, I listen carefully and try to understand the clients’ reality about leadership.
My question is:
What do you lead?
In my own reality, our obligation to lead is directed towards three main areas:
- organizations
- people
- ourselves (life leadership)
For each of those areas, there are again three things to consider:
- What matters
- Questions to ask
- What to achieve
In this sequence of postings, you can find some answers to those topics as stated by various leaders in all sorts of ranks and companies from SMBs to corporations.
Questions to ask when leading people
- Do I trust my team members?
- Do they trust me?
- Are my expectations clearly communicated and well understood? How do I know?
- Would my people be better off without me?
- Are my characteristics as a leader sufficient for my people to follow me?
- Is there anything else to do or to be to foster followship?
- Do my people understand me?
- Are they able to work autonomously?
- Do they follow the anticipated direction?
- Do I treat everyone the same in a fair way?
- What do my people expect from me?
- Do I understand my people?
- Do I give priority to my people’s problems or to organization requirements?
- Do others in the organization see myself as a human, social manager?
- Are they with me?
- Why are they with me?
- Will they continue to be with me?
- Do my people have trust in me, in good times and bad?
- Am I always honest?
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procarbazine is a chemotherapy medication used for the treatment of hodgkin’s lymphoma and brain cancers. for hodgkin’s it is often used together with chlormethine, vincristine, and prednisone while for brain cancers such as glioblastoma multiforme it is used with lomustine and vincristine. it is typically taken by mouth.
common side effect include low blood cell counts and vomiting. other side effects include tiredness and depression. it is not recommended in people with severe liver or kidney problems. use in pregnancy is known to harm the baby. procarbazine is in the alkylating agents family of medication. how it works is not clearly known.
procarbazine was approved for medical use in the united states in 1969. it is on the world health organization’s list of essential medicines, the safest and most effective medicines needed in a health system. in the united kingdom a month of treatment cost the nhs 450 to 750 pounds.
medical uses
when used to treat hodgkin’s lymphoma, it is often delivered as part of the beacopp regimen that includes bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine (tradename oncovin), prednisone, and procarbazine. the first combination chemotherapy developed for hodgkin’s lymphoma (hl), mopp also included procarbazine (abvd has supplanted mopp as standard first line treatment for hl, with beacopp as an alternative for advanced/unfavorable hl). alternatively, when used to treat certain brain tumors (malignant gliomas), it is often dosed as pcv when combined with lomustine (often called ccnu) and vincristine.
dose should be adjusted for kidney disease or liver disease.
side effects
very common (greater than 10% of people experience them) adverse effects include loss of appetite, nausea and vomiting. other side effects of unknown frequency include reduction in leukocytes, reduction in platelets, reduction in neutrophils, which can lead to increased infections including lung infections; severe allergy-like reactions that can lead to angioedema and skin reactions; lethargy; liver complications including jaundice and abnormal liver function tests; reproductive effects including reduction in sperm count and ovarian failure.
when combined with ethanol, procarbazine may cause a disulfiram-like reaction in some people.
it weakly inhibits mao in the gastrointestinal system, so it can cause hypertensive crises if associated with the ingestion of tyramine-rich foods such as aged cheeses; this appears to be rare.
procarbazine rarely causes chemotherapy-induced peripheral neuropathy, a progressive, enduring, often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs.
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